Tamoxifen Teva Tablet (Tamoxifen)

Package:

30 and 250 tablets of 10 mg each.

Indications:

Tamoxifen is a nonsteroidal antiestrogen. It is indicated in the palliative treatment of breast cancer.

Contraindications:

Contraindicated in sensitive individuals and in patients receiving coumarin-type anticoagulant therapy or with a history of deep vein thrombosis and pulmonary embolism.

Warnings:

Tamoxifen Teva should be used with caution in patients with leukopenia and thrombocytopenia. Caution should be exercised when using tamoxifen in patients with predisposing factors for clotting and vascular occlusion. Tamoxifen should not be used during pregnancy.

Side Effects:

Nausea, vomiting, hot flashes, thrombocytopenia, fatigue, leukopenia, hair loss, vaginal discharge, weight gain, thrombophlebitis, fractures, hypercalcemia, vaginal bleeding, dizziness, abnormal liver function tests, headache, vulvar pruritus, and depression have been reported.

Drug Interactions:

The potential for drug interactions should be considered due to the metabolism of tamoxifen in the liver. When used in combination with coumarin-type anticoagulants, there is a significant increase in the anticoagulant effect.

Dosage Recommendations:

The daily dose is 10-20 mg administered in the morning and evening. It can also be administered as a single dose of 20-40 mg per day. The initial response to treatment is usually achieved 1-3 months after initiation.