Each prefilled pen in 0.5 mg increments (0.5 mg to 30 mg in a single injection)

Contains 60 mg somatrogon in 1.2 mL solution giving doses Somatrogon recombinant DNA.

What is Ngenla and what is it used for?

Ngenla contains the active ingredient somatrogon, which is a modified form of human growth hormone.

Natural human growth hormone is essential for bone and muscle growth. It also helps your fat and muscle tissue develop in the right amounts.

Ngenla is used to treat children and adolescents over 3 years of age who do not have enough growth hormone and are not growing at a normal rate.

The active ingredient in Ngenla is produced using 'recombinant DNA technology'. This means that the substance is made in the laboratory in cells that have been modified to be able to produce this substance.

NGENLA treatment should be initiated and monitored by a physician specialized and experienced in the diagnosis and treatment of pediatric patients with growth hormone deficiency (GHD).

Patients should maintain their regular dosing day. If a dose is missed, somatrogon should be

administered as soon as possible within 3 days after the missed dose, and then the usual once weekly

dosing schedule should be resumed. If more than 3 days have passed, the missed dose should be

skipped and the next dose should be administered on the regularly scheduled day. In each case,

patients can then resume their regular once weekly dosing schedule.

Method of Application:

Somatrogon is administered by subcutaneous injection.

Somatrogon is applied to the abdomen, thighs, buttocks or upper arm area. Injection site per week

one should be replaced. Application to the upper arm and hip should be done by the caregiver.

Patients and caregivers are familiar with the application procedure for self-administration.

They must receive training to ensure they understand.

If more than one injection is required to administer the full dose, each injection should be administered at a different time.

It should be applied from the injection site.

Somatrogon is administered once a week, on the same day each week, at any time of the day.

NGENLA pre-filled pen dose from 0.5 mg to 30 mg in 0.5 mg (0.01 mL) increments.

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